I done some research on WPF client application development frameworks and eventually found out three most used framework and one yet to be mature framework. I thought its worth sharing the research result
1. Prism
http://compositewpf.codeplex.com/
Impression : Most advance framework
2. Caliburn
Impression : Advanced framework
3. Cinch
Impression : Solved particular set of problems and can be used along with other framework
4. WPF Application Framework (WAF)
Impression: Primitive and useful framework to develop MVVM pattern based application
All the application framework used MVVM pattern to develop the applications, I am sure this frameworks are worth learning and will definitely help us in career.